Even though most COPD-specific health status questionnaires show similar basic content, there is heterogeneity in the amount and quality of the items addressed. Numerous quality of life and/or health status questionnaire tools have been developed in an attempt to find an easy and reliable tool to use in every day clinical practice.
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This is mainly based on the fact that spirometry is only weakly associated with various health status questionnaires and does not give a real image of the COPD patients wellbeing. Recently, GOLD guidelines proposed health status, dyspnea measurement and number of exacerbations as key elements in addition to spirometry in order to manage and treat COPD. In every day practice COPD treatment and management guidance is currently largely based on the spirometric assessment. Patients with COPD often develop symptoms as dyspnoea, cough, phlegm, chest tightness, exercise intolerance, sleep and mental disorders as well as restriction of social activities. Quality of life is an important goal in COPD management that has been highlighted as a future research need from the recent International Primary Care Respiratory Group (IPCRG) research needs statement. Apart of its high mortality, one main concern for physicians is that COPD strongly impairs health status and quality of life. The CAT and CCQ have similar psychometric properties with a slight advantage for CCQ based mainly on patients’ preference and are both valid and reliable questionnaires to assess health status in COPD patients.Ĭhronic Obstructive Pulmonary Disease (COPD) is a prevalent disease in the general population and it has been estimated that it will be the fourth leading cause of death by the end of 2030. More than half of patients preferred CCQ instead of CAT.
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Patients suggested both CAT and CCQ as easier tools than SGRQ in terms of complexity and time considerations. The MCID calculated using the SEM method showed results similar to previous studies of 3.76 for the CAT, 0.41 for the CCQ and 4.84 for SGRQ. Both questionnaires exhibited a weak correlation with lung function (rho = −0.35 CAT and rho = −0.41 CCQ, p < 0.01). Patients with severe COPD reported worse health status compared to milder subgroups. Cronbach's alpha for both CAT and CCQ was high (0.86 and 0.89, respectively). Standard Error of Measurement (SEM) was used to calculate the Minimal Clinical Important Difference (MCID) of all questionnaires.
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Spirometry, 6 MWT, MRC scale, BODE index, and patients perspectives on questionnaires were recorded in all visits.
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We administered the CAT, CCQ and SGRQ in patients with COPD stage I-IV during three visits. We compared the usefulness and validity of the COPD Assessment Test (CAT) and the Clinical COPD Questionnaire (CCQ), two simple questionnaires, in comparison with the St. Health status provides valuable information, complementary to spirometry and improvement of health status has become an important treatment goal in COPD management.